Antidepressants were initially used in the treatment of depression. However, in the current scenario it is being used as a medication for anxiety and panic attacks too. Antidepressants can treat anxiety and mood related problems and thus they are effective in such matters. Antidepressants work on the principle that there are neurotransmitters in the brain like serotonin. And any changes in these brain chemicals can affect the moods and emotional state of a person. Lower serotonin in the brain can lead to symptoms of depression, mood changes and anxiety. Antidepressants are believed to increase the serotonin levels. This can lead to better mood and emotional state. Some of the popular classes of antidepressants that are used to treat depression are SSRI (Selective Serotonin Reuptake Inhibitors), TCA (Tricyclic antidepressants), and MAOI (Monoamine Oxidase Inhibitors). These treatments are effective and are commonly used in patients of depression, anxiety and panic disorders. However, a few common side effects of these medications include nausea, headache, sexual dysfunction, indigestion and insomnia. However, these side effects are temporary in nature and once the patient gets accustomed to the medications the side effects go away. According to the available studies, antidepressants decrease depression and help to reduce the symptoms as connected to depression for many patients. But in a few people it may cause very serious side effects including suicidal thoughts. It is important to talk to the doctor before taking antidepressant medications.