Norepinephrine and dopamine reuptake inhibitors or NDRIs are used to relive depression symptoms like irritability and sadness. There are certain chemicals in the brain which are called neurotransmitters which are related to depression. These include norepinephrine and dopamine. NDRI is one type of anti-depressant medication which helps raise the levels of these two neurotransmitters and thus enhance neurotransmission in general and thereby improve a person’s mood.

This medication although quite effective comes with several side-effects which include a person’s loss of appetite weight loss and headache. These particular side effects can greatly hamper a persons’ general well being and hinder his daily life. Dry mouth and skin rash is also a possibility for those taking up these medications. Excess sweating and an overall sense of shakiness and nervousness are also possible outcomes. Agitation and anxiety are also experienced by some who use this medication as well as constipation and stomach pains. Other side effects of this medication include muscle pains and sore throat, as well as nausea and vomiting. Some users also face trouble when sleeping.

These are among the major side effects that can come upon the users of NDRIs, so users must be aware of these problems before using it.