TCAs alter imbalances in the brain by altering the brain conditions with the aid of neurological stimulants. However advanced medical science and its inventions may be, this too is not a purely perfect cure for depressive diseases, meaning that they have certain side effects that cannot be ignored.

The side effects of TCAs can range from moderate to severe. Each side-effect threatens the natural metabolism of the biological equilibrium individuals. Some of the severe side effects include

• Suicidal or other self-destructive motives
• Drowsiness
• Dry mouth
• Blurred vision
• Constipation
• Urinary retention
• Dizziness
• Impaired sexual functioning
• Increased heart rate
• Disorientation or confusion
• Headache
• Low blood pressure
• Sensitivity to sunlight
• Increased appetite
• Weight gain
• Nausea
• Weakness

Different compounds in TCAs have specialized chemical structures and these organic compounds tend to destroy some cells more than others.

Some of the moderate to less prevalent side effects include:

• Lethargy
• Flu-like symptom

For best results, over-consumption of TCAs is discouraged and should not be taken over a period of 6 months. Also, it should only be given as an option to patients when psychotherapy and all other personal or familial supports or schemes fail.