St. John’s wort is a natural supplement extract which is has long been used as cures for illnesses including depression. However scientific researches are uncertain about its efficiency in treating severe depression over other anti-depressant drugs such as placebo. Such reasons are still subjected to more research and discovery by scientists. Recent analyses have shown that it has yielded unsatisfactory results when it came to counter chronic depression. However, it is known to successfully eliminate minor modes of depression as well as other standard antidepressant drugs and is also known to induce lesser side-effects. Depression conditions which science convinces that St. John’s wort cannot show beneficial results are:

• Chronic depression where people tend to feel constant despair which affects most activities in their daily life.
• Dysthymia is less serious but still a severe condition of depression which doesn’t overall impair daily activities yet has a substantial impact on them.
• No studies have shown St. John’s wort inducing any positive results in Bipolar disorder where people go through depression inked with frequent periods of mania.

However, people still use St. John’s wort as cure for major depression i.e. in Germany. However science studies clearly show its ineffectiveness to cope with symptoms materialized from chronic depression and there have only been rare cases where it has actually produced beneficial effects then anti-depressants.